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KMID : 0378019860290040071
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New Medical Journal
1986 Volume.29 No. 4 p.71 ~ p.76
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An histopathological and immunohistochemical study in the tingible body macrophages of the human lymph nodes
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Abstract
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.Lymph nodes and tonsiles of 20 cases with active tingible body macrophages were
examined by the peroxidase antiperoxidase (PAP) method using monospecific antibody against nervous system specific S-100 protein and Lysozyme.
The results obtained were as follows:
1. Tingible body macrophages of the germinal centers were devoid of the immunoreation products for S-100 protein and lysozyme.
2. The paracortical area of reactive lymph nodes showed a marked accumulation of S-100 protein containing dendritic shaped cells.
3. The detection S-100 protein in the nucleus and nuclear membrane suggested that interdigitating reticulum cells themselves synthesized S-100 protein.
These results showed a contrast between the tigible body macrophages and interdigitating reticulum cells, any macrophages by distributions of immunoreactive products for S-100 protein and lysozyme.
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KEYWORD
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